A duculator is used after you know how much static pressure you have to use. This is determined by the air handler/furnaces rated ESP minus all device pressure drops. Then you check the equivalent length of the duct fittings(els, take offs, boots, wyes, tees, etc), add that to the linear length to find your Total Equivalent Length(virtually no such thing as only a 100 foot duct system. You do this for both the supply and return duct and add them together. Then multiply ASP(available static pressure) times 100 and divide by the TEL, to find the friction rate to use.
EG: A 326' TEL duct system. .26X100=26, 26/326= .079" friction rate.
You can use it to see how much pressure a certain size duct will lose. However, there has to be enough pressure at the ducts beginning to move X amount of air.