Of course (ignoring any side winds or stack effects). However I don't know how many Pascals there are in 0.1" w.c.; I assumed that the poster was going to connect the duct to the furnace return and get somewhere between 0.1-0.2 w.c., and I don't understand why you think that the airflow would be negligible under those conditions. Whether it's enough or not for his house and # of occupants, and what is the resulting pressure in the house and if that's enough for radon mitigation are another matter.
Pstu, indeed you get more airflow with more pressure. The question is how much. This depends, amongst other things, on whether the flow is laminar or turbulent. For turbulent airflow, the pressure needed to get a certain airflow increases as the square of the desired airflow. So, as you increase pressure, the airflow does not increase in proportion -- you get less airflow than if the relationship was linear. It follows that if you decrease pressure, the airflow does not decrease in proportion either. You get more airflow than if the relationship was linear. It may be more obvious graphically. Draw a parabola y=square(x), where x is the airflow and y is the pressure. Pick a point on the curve representing a given airflow and pressure, then draw a straight line y=x from that point to coordinates 0,0. If you lower the air pressure while following the parabola the airflow is greater than if you follow the straight line. Hence my statement, you get more airflow at low air pressures than you would expect if the relationship was linear. For the sake of this argument I'm ignoring the non-turbulent airflow region.
I guess my point is, don't underestimate how much airflow 0.1" w.c. can generate...
Regards